There is a growing need for interception missile that can work above 35 km in order to cope with the threat from near-space hypersonic vehicles. The attitude control system employs six constant thrust on-off jets and only identifies the pulse on-off signals to track the target steadily. The pulse-width pulse-frequency (PWPF) is applied to make the continuous variable be equivalent to on-off variable. To overcome the interference, the attitude control system is designed using active disturbance rejection control (ADRC). The PWPF makes the continuous control signal be on-off signal and achieve controlling attitude of the missile. The simulation result shows that the output signal of the ADRC controller is more adaptive to be used with PWPF, and the ADRC controller has better rapidity and stability.